Some System Administrators like to change application prefixes around for security, organization and other reasons. Sometimes, being to quick for their fingers, they may forget a step in the install process. Once the source is ready for make, your configure options have already been parsed and saved. Running ./configure multiple times without a make clean could cause some unwanted behavior.
In this example, ./configure was run on Apache source without a --prefix. The second time we ran it, we included a prefix of /usr/local/apache-2.2. As you can see, the default prefix is /usr/local/apache2, which carried over to the second make instance of Apache.
/bin/sh /opt/httpd-2.2.22/srclib/apr/libtool --mode=install /usr/bin/install -c -m 755 libaprutil-1.la /usr/local/apache21/lib
libtool: install: error: cannot install `libaprutil-1.la' to a directory not ending in /usr/local/apache2/lib make[2]: \*\*\*
[install] Error 1 make[2]: Leaving directory `/opt/httpd-2.2.22/srclib/apr-util'
Don't be mean, use make clean If you are running configure more than once, make sure you use make clean between each ./configure, make and make install.
Enjoy!